Peyronie's Disease

Why choose HackensackUMC Urology?

The urologists at Hackensack University Medical Center are among the few area providers that have the expertise required to use a new FDA-approved medication to treat Peyronie’s disease.

Specially Trained

HackensackUMC’s urologists are specially trained to administer Xiaflex®, the only FDA-approved medication to treat Peyronie’s disease.


Our urologists are specially trained to administer a series of injections of a medication called Xiaflex®. The medication breaks down the scar tissue that causes curvature of the penis and is the most effective nonsurgical treatment available for Peyronie’s disease.

Symptoms and Causes

Peyronie’s disease is caused by scar tissue, or plaque, that forms inside your penis and causes it to curve upward or to the side. Although most men with Peyronie’s disease can have sex, the condition can sometimes cause erectile dysfunction or difficulty, embarrassment, or pain during sexual arousal and/or intercourse.

The condition can occur in men of any age, although it is more common in older men. Symptoms can appear overnight or develop slowly.

The cause of Peyronie’s disease is unknown, but some researchers believe that injury to the penis can cause a buildup of scar tissue that results in abnormal curvature. Other research suggests that Peyronie’s disease may be a genetic condition.

Individual Diagnosis and Treatment

Our experienced urologists will evaluate your condition and recommend a Peyronie’s disease treatment plan that may include medication or surgery.


Diagnosis and Treatment

Your urologist will conduct an exam to assess the severity and extent of the scar tissue and abnormal curvature in your penis. You should tell your doctor about any injury or trauma to your penis that occurred before you started to experience symptoms.

After a thorough assessment of your condition, your urologist will recommend the best treatment option for you. Mild cases of Peyronie’s disease usually do not require treatment, and some cases may improve on their own. If your condition requires treatment, there are several effective surgical and nonsurgical options available.

Nonsurgical Treatment Options
If your condition is moderate, causes some discomfort or affects your sex life, your doctor may recommend nonsurgical treatment, including:

  • Xiaflex® injections. Xiaflex is the only medication that is FDA-approved to treat Peyronie’s disease. The medication is administered into the scar tissue in your penis during a series of injections. Specialized training is required to administer Xiaflex injections, which are given in combination with brief exercises to gently stretch and straighten your penis.
  • Vitamin E supplements. Taking a daily vitamin E supplement may reduce swelling and prevent the buildup of scar tissue in the penis. Vitamin E therapy is convenient and inexpensive, but it may be less effective than other nonsurgical treatments.
  • Verapmil injections. • Verapamil is a medication for high blood pressure that is also used to treat scar tissue buildup. The medication is administered into the scar tissue in your penis during a series of injections to reduce abnormal curvature and pain caused by Peyronie’s disease.

Surgical Treatment Options
If your condition is severe, causes significant discomfort or affects your sex life, your doctor may recommend surgical treatment, including:

  • Penile plication. Plication involves using stitches to shorten the long side of the penis. Although this procedure can straighten the penis, it may result in overall size reduction of an inch or more.
  • Inflatable penile prosthesis. An inflatable plastic cylinder is implanted in your penis to help you get and maintain a straight erection.

Physicians in this Specialty




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